"Acyclovir" 200 mg (tablets): instructions for use, analogues of the preparation, composition and reviews

Viruses are the smallest pathogens,causing a variety of diseases. Especially dangerous are viruses that enter the cell, since it is impossible to destroy them - they are safely covered by the cell membrane. It was to combat them that the drug "Acyclovir" was created. For more than a decade, he and his counterparts have been prescribed for herpesviral diseases - human infection by a family of viruses that live in organisms of 90% of the world's population. Today we will review the drug "Acyclovir", instructions for use, price and reviews about it.

Herpesvirus family

The family consists of 8 viruses, among which:

1. Herpes 1 and 2 types.
2. Epstein-Barr
3. Cytomegalovirus.
4. Chicken pox virus
5. Herpes virus 6, 7 and 8 types.

These viruses live in the body for years, causinga number of concomitant diseases with weakened immunity of the patient. At the same time, a simple, it would seem, herpes, diagnosed practically by the entire population of our planet, no one sin. And it would be worthwhile, since it causes serious complications - some of its strains can even cause oncology. Today, doctors associate the family of herpesviruses with miscarriages, congenital malformations, immunodeficiency states. Fortunately, not all infections appear in such an aggressive form, because everything depends on the strain of the virus and the state of immunity. That is why herpes, if it has already got into the body, it is important to constantly monitor and prevent the reduction of the body's defenses.

What is Acyclovir?

"Acyclovir" is a synthetic analogacyclic purine nucleoside (DNA component). The main function of the drug is the antiviral effect, which "Acyclovir" selectively shows against herpes viruses. It is introduced into the cell (in which the virus has already "sat down"), binds to its enzymes and violates the DNA of the virus, which prevents its reproduction. In this case, the preparation practically does not influence the cells of the carrier of infection. On sale there is a drug with additions in the names - "Acry", "Herd", "Agos". This is the same tool, but different manufacturers and in different forms of release. So, "Acyclovir 200 Herds" (instruction and analogues of the drug we will consider today) is a German remedy, the price of which is much lower than Russian and Ukrainian. It is a big plus by itself.

"Acyclovir" (200 mg in tablets, instruction -below) prevents the development of visceral complications. The drug also has an immunomodulatory effect. It is strong immunity that suppresses intracellular viruses and does not allow them to manifest themselves.

"Acyclovir-Acos" (200 mg in tablets), instructionwhich we are considering today, is only partially absorbed into the gastrointestinal tract. Most of it in unchanged form is excreted in the urine. With renal failure, the elimination half-life increases severalfold.

Instructions for the use of "Acyclovir" (200 mg)

So let's understand. At what diseases apply "Acyclovir" (200 mg)? Instruction for use reads:

1. With herpes skin and mucous membranes, both primary and in the phase of exacerbation.
2. With genital herpes.
3. When depriving of shingles.
4. When chickenpox in the first day after the appearance of the rash.
5. With cytomegalovirus.
6. Patients with severe immunodeficiency caused by chemotherapy, HIV infection, reception of immunity-suppressing agents, for the prevention of infections that cause herpes simplex.

The drug is used both for the prophylaxis of herpesvirus infections, and for their neglected form. The difference is only in the dosage.

Structure of the preparation

Note. "Acyclovir" 200, whose composition is characterized by a minimum of components, is made on the basis of a synthetic analogue of the nucleic nucleoside and additional components - potato starch, microcrystalline cellulose, croscarmellose sodium, polyvinylpyrrolidone, colloidal and magnesium dioxide, stearate.

The drug contains lactose in its shell, therefore it is not recommended for people with hypersensitivity to it. However, in this case, cream and powder for the preparation of injections are on sale.

Is Acyclovir harmful?

The answer is ambiguous. Like other antiviral drugs, "Acyclovir" 200 mg (tablets, the instruction of which we are discussing today) is capable of causing side effects. At application nausea, vomiting, a diarrhoeia, excessive fatigability, a headache, an allergic reaction to structure of a preparation are possible.

With intravenous administration, indicatorsblood - urea and creatinine, bilirubin. Enzymes of the liver are increased. People who suffer from kidney disease should take Acyclovir especially carefully, since it negatively affects their work. Therefore, such patients need a dose adjustment.

Usually, "Acyclovir" (200 mg in tablets), ininstructions are indicated, well tolerated and non-toxic to the body. But taking it constantly to oppress herpesviruses is impossible - it is harmful to the liver. In addition, over time, the viruses get used to the drug, and it stops helping.

In what forms is Acyclovir sold?

In pharmacies "Acyclovir" can be found in 3 forms:

1. Ointment. Local application is especially popular for the treatment of the notorious "cold" on the lips.
2. Pills. For the treatment of more "in-depth" herpes.
3. Powder for the preparation of intravenous injections.

In this case, the most popular "Acyclovir" in tablets (200 mg). Instructions for use are discussed below. And in the form of ointments.

"Acyclovir" in tablets

The drug is available in packs of 20 tablets. The method of application depends on the diagnosis and age.

Prevention. 1 tablet 4 times a day.

A simple herpes virus. 1 tablet 5 times a day.

Shingles. 4 tablets 5 times a day.

For adults and children over the age of two, the dosage is similar.

With renal failure, "Acyclovir" is used for 200 mg 2 times a day at intervals of 12 hours.

Duration of treatment is usually 5 days (with shingles - 8). For the prevention of genital herpes, "Acyclovir" is used from six months to a year.

Attention! Pills drink plenty of water and do not drink them at night.

Cost of preparation

"Acyclovir" (tablets 200 mg), instructions and pricewhich can be found in almost every pharmacy, is quite affordable. The cost of it in Russian rubles is from 60 to 200 rubles. The price depends not only on the number of tablets in the package, but also on the manufacturer. So, "Acyclovir-Farmak", tablets of 200 mg, 20 pieces, produces the Ukrainian pharmaceutical company, so its cost is very low - 20-30 UAH.

"Acyclovir" in powder

Powder for the preparation of injections in the lasttime is very rare. Children from 12 years and adults of 5-10 mg per 1 kg of body weight with an 8-hour interval. The maximum dose taken per day is 30 mg / kg. With intravenous administration, it is possible to develop additional side reactions that are not observed when taking tablets - hallucinations, drowsiness, tremor, kidney complications, convulsions, psychosis.

"Acyclovir" for external use

The cream is prescribed for external use whensuch manifestations of herpes as a "cold" on the lips, a rash in the genital area with genital herpes, localized shingles. This cream effectively removes the manifestation of the virus on the skin, penetrating the epidermis into the affected cells. Almost does not enter the systemic circulation. Thus, the agent prevents the formation of new elements of the rash, reduces pain in herpes zoster. In this case, the cream is not recommended to apply to the mucous membranes of the mouth, nose, vagina. The price is 20-40 UAH. (in Russia - 150 rubles).

Eye ointment "Acyclovir" is used forkeratitis of herpesvirus etiology and for the prevention of "colds" on the lips. The agent is applied to the affected areas up to 6 times a day. The course of treatment is 5-10 days. It is important to start it as soon as possible. In this case, "Acyclovir" is more effective.

special instructions

"Acyclovir" is not prescribed to pregnant women due toInsufficiency of data on its safety for expectant mothers. In this case, during the lactation period, it is contraindicated, since it is partially excreted with milk. If there is an acute need for a prescription, the child's milking is canceled.

People with kidney failure"Acyclovir-Acry" in tablets 200 mg (in the instructions for use above it was indicated) should be administered cautiously. With the simultaneous administration of medication with nephrotoxic drugs, renal dysfunction is possible. In the elderly, especially with concomitant diagnosis, it is recommended to drink water in large quantities.

"Acyclovir" is not recommended to be combined with alcohol(although there is no direct data on its interaction with alcohol), because, like any other antiviral, in combination with them, the drug is able to cause allergies, kidney damage, etc.

Is it possible to apply the drug to a child?

Since the effect of "Acyclovir" 200 mg in tablets(instruction for children will be described below) on the body of infants is not studied, it is not recommended to give it to children for up to a year. When a disease is caused by chickenpox, it is administered either orally or externally. But up to a year children very seldom are ill with this illness. Ointment for relief of symptoms of herpes is shown to children from 1 month.

Apply according to the following scheme:

• 1-2 years - 100 mg / day 4 times a day (5 days).
• after 2 years - 200 mg 4 times a day.
• 2-5 years - 400 mg 4 times a day.
• after 6 years - 800 mg 4 times a day.

In severe cases, the drug is used up to 10 days.As an alternative treatment for the prevention of recurrence, 400 mg of medication every 12 hours is indicated. "Acyclovir", instruction on the use of 200 mg tablets confirms this, they are prescribed to children. But it is better to consult a doctor beforehand.

Drug analogues

Preparations with acyclovir in the basic composition that fight with herpesvirus:

1. "Acyclovir sandoz" (German cream with herpes rashes).

2. "Acyclovir beluga" (tablets).

3. "Zovirax" (powder for the preparation of injections, tablets).

4. "Virolex" (available in the form of powder, tablets, eye ointment and cream).

5. "Medovor" (powder for the preparation of solution).

6. "Vivorax" (cream and ointment).

7. "Gerpevir" in tablets.

Each of these drugs has one active substance, but with different components of additional composition. It is important to know people with certain types of food intolerance.

What are the responses about Acyclovir?

Given the prevalence of the herpes virus, experienceMany people took the drug. Most he approached, as the substance acyclovir is usually well tolerated and rarely causes side effects. Consider the feedback on it in more detail. For a start about the benefits.

1."Acyclovir" refers to the first generation of antiviral drugs, therefore, it is distinguished by a low price compared to other drugs of this series. More advanced drugs are distinguished by high prices, but they have fewer side effects.

2.Efficiency is another undoubted advantage. "Acyclovir" helps very quickly, in a few days, to eliminate the symptoms of herpes. Moreover, due to its immunomodulatory properties, herpes for a long time does not disturb the patient.

3. "Acyclovir" is used not only for herpes.Practice shows that it is effective against viruses that cause colds and flu, as well as rotavirus. After taking Acyclovir, the fever quickly falls, and the patient as a whole is on the mend. However, it is better to apply it for a flu on the recommendation of a doctor.

And now pay attention to the shortcomings, which, despite the abundance of positive feedback, are still present.

1. "Acyclovir" does not help everyone. In case of its ineffectiveness, either another herpes treatment regimen or another antiviral drug is needed. This is due to the individual characteristics of the body.
2. Side effects.The instructions indicate quite a few side effects, which, fortunately, are rare, but the risk of their appearance, especially when overdosed, is present. It is especially cautious to take this drug with kidney disease, in particular, with kidney failure.
3. Sometimes one "Acyclovir" for the treatment of herpesis not enough. Herpes disappears, but then quickly appears again. This suggests the need to improve immunity immunomodulators. Or, again, the need to select another antiviral drug.

Finally

In general, "Acyclovir" and its analogs are goodare transferred and differ in efficiency. The shortcomings, of course, are much less than the benefits, which explains the popularity of the drugs. At the same time, many complain that doctors began to write it out less and less. Perhaps this is due to the growing popularity of more expensive means.